Characterization of skin tissue heterogeneity with near-infrared microspectroscopy and its effects on noninvasive measurements of glucose

نویسنده

  • Natalia Victorovna Alexeeva
چکیده

Approved: __________________________ Thesis Supervisor __________________________ Title and Department __________________________ Date CHARACTERIZATION OF SKIN TISSUE HETEROGENEITY WITH NEAR-INFRARED MICROSPECTROSCOPY AND ITS EFFECTS ON NONINVASIVE MEASUREMENTS OF GLUCOSE by Natalia Victorovna Alexeeva A thesis submitted in partial fulfillment of the requirements for the Doctor of Philosophy degree in Chemistry in the Graduate College of The University of Iowa

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Impact of tissue heterogeneity on noninvasive near-infrared glucose measurements in interstitial fluid of rat skin.

BACKGROUND Movement of the optical interface used to collect noninvasive near-infrared spectra is known to dramatically increase prediction errors for glucose concentration measurements within the interstitial fluid of living rat skin. Prediction errors increase by more than 2.5-fold when the interface is moved before each non-invasive measurement compared to measurements where the interface po...

متن کامل

FTIR Determination of Miconazole Effects on Mice Fetus Brain Tissue

Miconazole is an imidazole antifungal agent, commonly applied topically to the skin or mucous membranes. The aim of this study was to examine the alternative method for gaining mechanism or the bimolecular changes caused by the possible teratogenic effects of Miconazole on mice fetus brain tissue using FTIR-Microspectroscopy. The mice were injected with Miconazole (60 mg/Kg) on gestation day 9....

متن کامل

Rapid near-infrared Raman spectroscopy system for real-time in vivo skin measurements.

A rapid dispersive-type near-infrared (NIR) Raman spectroscopy system and a Raman probe were developed to facilitate real-time, noninvasive, in vivo human skin measurements. Spectrograph image aberration was corrected by a parabolic-line fiber array, permitting complete CCD vertical binning, thereby yielding a 3.3-16-fold improvement in signal-to-noise ratio. Good quality in vivo cutaneous NIR ...

متن کامل

Noninvasive near infrared spectroscopy on living tissue with multivariate calibration approaches

Near infrared (NIR) spectroscopy is being developed on living tissue models for noninvasively measuring in vivo glucose concentrations in individuals with diabetes. Multivariate calibration models have been built and the selectivity of each multivariate signature has been evaluated by several means. The primary objective of the research detailed in this dissertation is to practically apply noni...

متن کامل

Non-Invasive Determination of Blood Glucose Levels by Optical Waveguide

Objective: Today, there are various non-invasive techniques available for the determination of blood glucose levels. In this study, the level of blood glucose was determined by developing a new device using near-infrared (NIR) wavelength, glass optical waveguide, and the phenomenon of evanescent waves. Materials and Methods: The body's interstitial fluid has made possible the development of ne...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016