Combination dual responsive polypeptide vectors for enhanced gene delivery.
نویسندگان
چکیده
Variation in amino acid sequences on a disulfide-linked polypeptide backbone generates differing pK(a) vectors for DNA delivery, which release nucleic acids under reducing conditions and transfect cells with greater efficacy than non-reducible or non-variable pK(a) analogues.
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عنوان ژورنال:
- Molecular bioSystems
دوره 4 7 شماره
صفحات -
تاریخ انتشار 2008