Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.

نویسندگان

  • Siaw Eng Ho
  • Geetha Subramaniam
  • Selvi Palasubramaniam
  • Parasakthi Navaratnam
چکیده

We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 46 10  شماره 

صفحات  -

تاریخ انتشار 2002