pH-dependent binding of guests in the cavity of a polyhedral coordination cage: reversible uptake and release of drug molecules† †Electronic supplementary information (ESI) available: Experimental information; further details on the NMR titrations used to measure binding constants at different pH values; crystallographic data in CIF format (CCDC 1013340). See DOI: 10.1039/c4sc02090a Click here for additional data file. Click here for additional data file.
نویسندگان
چکیده
For all host/guest binding experiments samples were prepared as follows. Host solution: the host cage (16 mg) was dissolved in 10 ml D2O to make a 0.2 mM stock solution. Guest solutions: the guests were individually dissolved in 5 ml of the host solution (to keep the host concentration constant during the titration); the mass used varied with the desired concentration. All binding experiments were performed three separate times; the values for binding constants quoted are the average of the three measurements with the error quoted being two standard deviations from the mean.
منابع مشابه
Mutual stabilisation between MII 4L6 tetrahedra and MIIX4 2– metallate guests† †Electronic supplementary information (ESI) available: Full experimental procedures, NMR, ESI-MS and UV-Vis spectra and details of the calculated void volumes and CIFS. CCDC 1047195–1047198. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc01083g Click here for additional data file. Click here for additional data file.
متن کامل
Imposing control on self-assembly: rational design and synthesis of a mixed-metal, mixed-ligand coordination cage containing four types of component† †Electronic supplementary information (ESI) available: Synthesis of the cage complex; bond distances and angles around the metal ions; COSY and DOSY NMR data; and high resolution electrospray mass spectral expansion for the cage. CCDC 1425635. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc03526k Click here for additional data file. Click here for additional data file.
متن کامل
PdII 2L4-type coordination cages up to three nanometers in size† †Electronic supplementary information (ESI) available: Synthetic procedures and experimental details. CCDC 1511090–1511096. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6sc04732g Click here for additional data file. Click here for additional data file.
متن کامل
Reversible quantitative guest sensing via spin crossover of an iron(ii) triazole† †Electronic supplementary information (ESI) available: Synthetic details, NMR spectra, instrumentation, plus additional structural, magnetic and TGA information and diagrams. CCDC 1434103 and 1434104. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5sc04583e Click here for additional data file. Click here for additional data file.
متن کامل
Efficient stabilisation of a dihydrogenphosphate tetramer and a dihydrogenpyrophosphate dimer by a cyclic pseudopeptide containing 1,4-disubstituted 1,2,3-triazole moieties† †In memoriam Fritz Vögtle (1939–2017). ‡ ‡Electronic supplementary information (ESI) available: Synthetic details, NMR spectroscopic and MS spectrometric characterisation of 2, NMR spectroscopic and mass spectrometric binding studies, ITC titrations, and crystal structures. CCDC 1555955–1555958. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc02700a Click here for additional data file. Click here for additional data file.
متن کامل
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2015