Biologically aggressive regions within glioblastoma identified by spin-lock contrast T1 relaxation in the rotating frame (T1ρ) MRI
نویسندگان
چکیده
Spin-lattice relaxation in the rotating frame magnetic resonance imaging allows for the quantitative assessment of spin-lock contrast within tissues. We describe the utility of spin-lattice relaxation in the rotating frame metrics in characterizing glioblastoma biological heterogeneity. A 84-year-old man presented to our institution with a right frontal temporal mass. Prior tissue sampling from a peripheral nonenhancing lesion was nondiagnostic. Stereotactic image-guided tissue sampling of the nonenhancing T2-fluid-attenuated inversion recovery hyperintense region involving the anterior cingulate gyrus with elevated spin-lattice relaxation in the rotating frame metrics provided a pathologic diagnosis of glioblastoma. This case illustrates the utility of spin-lattice relaxation in the rotating frame magnetic resonance imaging in identifying biologically aggressive regions within glioblastoma.
منابع مشابه
Accuracy and Precision in Quantitative Rotating Frame Relaxometry at High and Ultra-High Magnetic Fields
Purpose: This work is based on the review of novel MRI methods for generating the longitudinal relaxation contrast, T1ρ, and the transverse relaxation contrast, T2ρ in the rotating reference frame regime at high and ultra-high magnetic fields. Clinical application of the T1ρ and T2ρ contrasts using the onor off-resonance spin-lock (SL) radiofrequency (RF) irradiation has been a challenging task...
متن کاملCharacterization of non-hemodynamic functional signal measured by spin-lock fMRI
Current functional MRI techniques measure hemodynamic changes induced by neural activity. Alternative measurement of signals originated from tissue is desirable and may be achieved using T1ρ, the spin-lattice relaxation time in the rotating-frame, which is measured by spin-lock MRI. Functional T1ρ changes in the brain can have contributions from vascular dilation, tissue acidosis, and potential...
متن کاملT1ρ imaging: Techniques and Basis for Image Contrast
Introduction Nuclear spin relaxation plays a key role in imparting image contrast in magnetic resonance imaging (MRI). Traditionally, T1 (spin-lattice relaxation) and T2 (spin-spin relaxation) relaxation times and magnetization transfer (MT) contrast are exploited to better visualize a given tissue in a specific pathology. In recent years, T1ρ (spin-lattice relaxation in the rotating frame) is ...
متن کاملSpin Locked Steady-State Free Precession Imaging
Introduction: T1ρ MRI is typically performed by magnetization preparation followed by a readout sequence during which the T1ρ-weighted signal is frequency and phase encoded (1). This paradigm is inherently time inefficient and, instead, it might be desirable to continuously acquire the T1ρ-weighted signal in the steady-state. Unfortunately, it isn’t clear how to establish a steady-state T1ρ con...
متن کاملIn vivo chronic myocardial infarction characterization by spin locked cardiovascular magnetic resonance
BACKGROUND Late gadolinium enhanced (LGE) cardiovascular magnetic resonance (CMR) is frequently used to evaluate myocardial viability, estimate total infarct size and transmurality, but is not always straightforward is and contraindicated in patients with renal failure because of the risk of nephrogenic systemic fibrosis. T2- and T1-weighted CMR alone is however relatively insensitive to chroni...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 12 شماره
صفحات -
تاریخ انتشار 2017