Immunization against leptospirosis: vaccine trials with heat-killed whole cell and outer envelope antigens in hamsters.
نویسندگان
چکیده
Heat-killed whole cell and outer envelope antigens prepared from homologous virulent and avirulent strains of Leptospira serotypes canicola and pomona were evaluated for protecting hamsters against experimental leptospirosis. The heat-killed bacterins proved at least as effective as the outer envelope antigens, or more so, in providing protection against death and infection, and they are easier and more economical to prepare.
منابع مشابه
Immunization against leptospirosis: continued vaccine trials in hamsters using strains isolated from Barbados.
Heated whole-cell suspensions of L. interrogans serotype copenhageni strains isolated from the field in Barbados have proved to be protective immunogens against experimental leptospirosis.
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عنوان ژورنال:
- Bulletin of the Pan American Health Organization
دوره 10 2 شماره
صفحات -
تاریخ انتشار 1976