Thoracoscopic ethanol injection and radiofrequency ablation for the treatment of hepatocellular carcinoma located immediately under the diaphragm.
نویسندگان
چکیده
We previously reported that the combination therapy of percutaneous ethanol injection and radiofrequency ablation (PEI-RFA) was more effective than RFA alone in inducing wider coagulated necrosis for the treatment of hepatocellular carcinoma (HCC). In the present study, we thoracoscopically applied the combination therapy to the treatment of HCC located immediately under the diaphragm. RFA electrode and ethanol injection needle were inserted into the tumor through the right side of the diaphragm in 6 patients with HCC close to the diaphragm. In all cases, the tumor was completely ablated with enough safety margin around the tumor. No local tumor recurrence has been observed in a relatively short-time follow-up period. The volume of coagulated necrosis and the energy requirement for coagulation in thoracoscopic ethanol injection and RFA (T-EI-RFA) were comparable to those of PEI-RFA. Although HCC located immediately under the diaphragm is difficult to treat with a percutaneous approach due to the poor visualization by ultrasonography, T-EI-RFA is considered to be an effective treatment modality.
منابع مشابه
Thoracoscopic Treatment of Massive Hemorrhagic Complication Due to Diaphragm Injury after Radiofrequency Ablation of Hepatocellular Carcinoma
The clinical application of radiofrequency ablation (RFA) of hepatic tumor has gradually been accepted as an effective and safe method for the treatment of small hepatic malignant tumors. However, the potential complications were often overlooked. We report a case of hepatitis C related hepatocellular carcinoma (HCC), who developed a massive hemothorax after a RFA procedure for treatment of rec...
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Background. Transarterial chemoembolization alone or in association with radiofrequency ablation is an effective bridging strategy for patients with hepatocellular carcinoma awaiting for a liver transplant. However, cost of this therapy may limit its utilization. This study was designed to evaluate the outcomes of a protocol involving transarterial embolization, percutaneous ethanol injection, ...
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عنوان ژورنال:
- International journal of oncology
دوره 29 2 شماره
صفحات -
تاریخ انتشار 2006