New presence in the EMBnet Brazilian Node

نویسندگان

  • Ana Tereza Ribeiro Vasconcelos
  • Goran Neshich
  • Wim Degrave
چکیده

Designing a new drug is not a trivial project and very often it demands large amounts of money and time. The proteins and their interactions play important role in this scientific sector. The main approach of drug designing is to create new molecules which could affect a biological mechanism with the minimum side effects possible. In this review, we present the different kinds of protein interactions and their main depositories which are the online protein databases. Moreover, the main computational techniques that are being used in designing drug targets are presented. The combination of computational approaches with the biological ones demonstrates the important role that bioinformatics is playing in drug designing and targeting.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Swiss EMBnet node web server

EMBnet is a consortium of collaborating bioinformatics groups located mainly within Europe (http://www.embnet.org). Each member country is represented by a 'node', a group responsible for the maintenance of local services for their users (e.g. education, training, software, database distribution, technical support, helpdesk). Among these services a web portal with links and access to locally de...

متن کامل

Protein frustratometer: a tool to localize energetic frustration in protein molecules

The frustratometer is an energy landscape theory-inspired algorithm that aims at quantifying the location of frustration manifested in protein molecules. Frustration is a useful concept for gaining insight to the proteins biological behavior by analyzing how the energy is distributed in protein structures and how mutations or conformational changes shift the energetics. Sites of high local frus...

متن کامل

Inhibitory effects of Urtica dioica L. root on electrophysiological properties of isolated rabbit atrioventricular node

Background and objectives: The ideal drug for treatment of a wide range of supraventricular arrhythmia hasn't yet been developed. Previous studies have shown antihypertensive and negative inotropic effects of the Urtica dioica L. (nettle). Therefore, the aim of present study is to determine the rate dependent inhibitory effects of ethanol extract of nettle roo...

متن کامل

PATH: a task for the inference of phylogenies

UNLABELLED Phylogenetic Analysis Task in Husar (PATH) is a task for the inference of phylogenies. It executes three phylogenetic methods and automatically chooses the evolutionary model for each set of data. The output of the tasks shows the consensus trees together with full results obtained from all executed methods. AVAILABILITY PATH is available at the German EMBnet node after registratio...

متن کامل

Evolutionary Computing Assisted Wireless Sensor Network Mining for QoS-Centric and Energy-efficient Routing Protocol

The exponential rise in wireless communication demands and allied applications have revitalized academia-industries to develop more efficient routing protocols. Wireless Sensor Network (WSN) being battery operated network, it often undergoes node death-causing pre-ma...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2007