Role of C-reactive protein as a marker for microalbuminuria in type 2 diabetics.

BACKGROUND One of the most important complications of Type 2 diabetes mellitus is diabetic nephropathy which is reported as the leading cause of premature deaths due to renal failure. This study was being conducted to see the role of C-reactive protein a marker in type 2 diabetic patient with micro-albuminuria. METHODS This cross sectional study was carried out in the Diabetic Clinic of Pakistan Medical Research Council, Research Centre Lahore. Personal history about the disease was collected on a questionnaire. Blood and urine sample of 50 type 2 diabetic patients between the ages of 40-65 years were collected to analyze C-reactive protein and micro-albuminuria respectively. Data were analyzed using SPSS-15. The Pearson correlation coefficient test was used to determine correlation between urine albumin and C-reactive protein. RESULTS There were 22 micro- albuminuria positive cases out of total 50 diabetic cases. Of these 14 (63%) showed raised C-reactive protein levels (p < 0.00). CONCLUSION There is significant association between the level of serum C- reactive proteins and micro-albuminuria in type 2 diabetics.