Author’s response to reviews Title: A study of the association of rs12040273 with susceptibility and severity of coronary artery disease in a Chinese Han population Authors:

Title: A study of the association of rs12040273 with susceptibility and severity of coronary artery disease in a Chinese Han population Authors: Bo Yang ([email protected]) Shan Yan ([email protected]) Jianjun Yan ([email protected]) Yafei Li ([email protected]) Mohammad Reeaze Khurwolah ([email protected]) Liansheng Wang ([email protected]) Zhong Chen ([email protected]) Version: 3 Date: 06 Jan 2018 Author’s response to reviews: Our response letter 1. Please edit the section „Ethics approval and consent to participate‟ to indicate whether informed consent was written or verbal. If verbal, please state the reason and whether the ethics committee approved this procedure. If the need for consent was waived by an IRB or is deemed unnecessary according to national regulations, please clearly state this, including the name of the IRB or a reference to the relevant legislation. Our response: we added these information. Yes,all participants gave their written consent.