Synchronization between patches of local excitation in a cerebellar granular layer model

In a model of the cerebellar granular layer, pairs of neurons aligned along the parallel "ber axis "red synchronized over long distances provided the a!erent mossy "bers were spatially uniformly excited. Here, we applied a nonuniform mossy "ber input pattern and found that local patches of increased granule cell activity were sharpened by the feedback inhibition which granule cells received from Golgi cells. These local patches maintained their own rhythm, or synchronized with each other, depending on the distance between them and on their absolute and relative levels of activity. 2001 Elsevier Science B.V. All rights reserved.