Two new roridins isolated from Myrothecium sp.
نویسندگان
چکیده
CH2C12. The active fractions (CC14 and CH2C12, 300mg) were pooled and subjected to a flash silica column (CHCI3 : MeOHstep gradient). The active fraction (52 mg) eluted with 95:5 CHC13:MeOHand was subjected to a second flash silica column (hexanes : EtOAc step gradient). Final purification was obtained by normal phase HPLC (Sigma-Aldrich Nucleosil Silica 5 ,am, 25.0 cmX4.6 mm) with a solvent system of 3:2 hexanes:EtOAc (flow rate=1.0ml/minute) yielding 2.85mg 1 (Rt 8.8 minutes)
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عنوان ژورنال:
- The Journal of antibiotics
دوره 54 6 شماره
صفحات -
تاریخ انتشار 2001