Systemic distribution of 14C-formaldehyde from formocresol-treated pulpotomy sites.
نویسندگان
چکیده
Formocresol is currently the most popular agent for performing pulpotomies on primary teeth. HistOl'3gical evaluation offonnocresol-treated pu'.... tissue reveals inflammation and necrosis.4 ,5,6,8,11.1S Formocresol has been demonstrated to be toxic to connective tissue.16•18 In vitro, formaldehyde will diffuse through the apical foramen within minutes after placing formocresol in the root canal. 1 9 In spite of these findings, formocresol remains popular because of its high incidence of clinical success.l ·9 In a study using Rhesus monkeys, 14C_ formaldehyde was found to be absorbed into the systemic circulation within minutes after performing a formocresol pulpotomy.20 The volume of distribution of the 14C-formaldehyde was larger than the volume of the monkeys, suggesting that either tissue binding or metabolic breakdown of the 14C-formaldehyde occurred.20 The purpose of this study was to determine the fate of the 14C-formaldehyde which is absorbed following its application to pulpotomy sites.
منابع مشابه
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عنوان ژورنال:
- Journal of dental research
دوره 59 3 شماره
صفحات -
تاریخ انتشار 1980