Inhibition of anandamide hydrolysis attenuates nociceptor sensitization in a 5 murine model of chemotherapy-induced peripheral neuropathy
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چکیده
Running Head: URB597 attenuates nociceptor sensitization 14 15 16 17 18 19 Corresponding author: 20 Donald A. Simone 21 University of Minnesota 22 School of Dentistry 23 Dept. of Diagnostic & Biological Sciences 24 515 Delaware St. SE 25 Minneapolis, MN 55455 26 TEL: 612-625-6464 27 FAX: 612-626-2651 28 Email: [email protected] 29 Articles in PresS. J Neurophysiol (December 10, 2014). doi:10.1152/jn.00692.2014
منابع مشابه
Inhibition of anandamide hydrolysis attenuates nociceptor sensitization in a murine model of chemotherapy-induced peripheral neuropathy.
Painful neuropathy frequently develops as a consequence of commonly used chemotherapy agents for cancer treatment and is often a dose-limiting side effect. Currently available analgesic treatments are often ineffective on pain induced by neurotoxicity. Although peripheral administration of cannabinoids, endocannabinoids, and inhibitors of endocannabinoid hydrolysis has been effective in reducin...
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تاریخ انتشار 2014