1 2 The involvement of reactive oxygen species in long - term potentiation 3 in the spinal cord dorsal horn 4 5 6 Kwan
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چکیده
2 The involvement of reactive oxygen species in long-term potentiation 3 in the spinal cord dorsal horn 4 5 6 Kwan Yeop Lee, Kyungsoon Chung, Jin Mo Chung 7 8 9 Department of Neuroscience and Cell Biology, University of Texas Medical Branch, 10 301 University Boulevard, Galveston, TX 77555-1069, USA 11 12 13 14 15 16 17 Running title: ROS in spinal cord LTP 18 19 20 21
منابع مشابه
Involvement of reactive oxygen species in long-term potentiation in the spinal cord dorsal horn.
Recent studies suggest that reactive oxygen species (ROS) are functional messenger molecules in central sensitization, an underlying mechanism of persistent pain. Because spinal cord long-term potentiation (LTP) is the electrophysiological basis of central sensitization, this study investigates the effects of the increased or decreased spinal ROS levels on spinal cord LTP. Spinal cord LTP is in...
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5-hydroxytryptamine (5-HT) is released in spinal cord by descending systems that modulate somatosensory transmission and can potently depress primary afferent-evoked synaptic responses in dorsal horn neurons. Since primary afferent activity-induced long-term potentiation (LTP) may contribute to central sensitization of nociception, we studied the effects of 5-HT on the expression of sensory-evo...
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تاریخ انتشار 2009