Primate type-C virus-related reverse transcriptase and RNA in human acute leukemia cells as potential diagnostic markers.
نویسندگان
چکیده
Human acute leukemic blood cells contain ribonucleic acid (RNA) and reverse transcriptase which are specifically related to analogous components in type-C viruses isolated from a lymphomosarcoma and from a fibrosarcoma which developed spontaneously in two different subhuman primate species. By appropriately using molecular probes specific for these viral components, it may be possible to detect human leukemic cells or, perhaps, pre-leukemic alterations of human blood cells, with much greater sensitivity than by current diagnostic methods.
منابع مشابه
Relationship between RNA-directed DNA polymerase (reverse transcriptase) from human acute leukemic blood cells and primate type-C viruses.
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عنوان ژورنال:
- Annals of clinical and laboratory science
دوره 4 5 شماره
صفحات -
تاریخ انتشار 1974