An opportunity to intervene: erythropoietin for the treatment of anaemia in pre-dialysis patients.
نویسندگان
چکیده
17. Feng L, Xia Y, Tang W, Hwang D, Wilson C. Expression of cyclooxygenase (COX)-l, COX-2, and cytosolic phopspholipase A2 (cPLA2) in anti-GBM antibody (Ab) glomerulonephritis (GN) (abstract). J Am Soc Nephrol1993; 4: 452 18. Komhoff M, Grone HJ, Klein T, Seyberth HW, Nusing RM. Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: implication for renal function. Am J Physiol 1997; 272: F460-F468 19. Schneider A, Wolf G, Reszka M, Thaiss F, He1mchen U, Stahl RAK. Cyclooxygenase-2 inhibition enhances glomerular mesangia1 cell proliferation in a rat model of renal ablation (abstract). Am Soc Nephrol1997; S605 20. Schneider A, Jocks T, Wenzel U, Reszka M, He1mchen U, Stahl RAK. Prostaglandin G/H synthase (PGHS) inhibitors modulate glomerular MCP-1 mRNA expression in anti-Thy-I antiserum (ATS) induced glomerulonephritis (abstract). J Am Soc Nephrol 1996; 7: A2365
منابع مشابه
PHARMA COKINETICS OF RECOMBINANT ERYTHROPOIETIN AND RED CELL METABOLISM IN HAEMODIALYSIS PATIENTS
The pharmacokinetics of recombinant human erythropoietin (rHuEpo) administered intravenously has been investigated in a group of five patients with chronic renal failure who were dialysis-dependent. The half-life of circulating erythropoietin decreased from 7.9±OA hr (mean ±SO) at the beginning of treatment to 6.2±O.6 hr after 6 weeks and 5A±O.9 hr after 4 months of treatment. In spite of t...
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Background and Objective: Anemia is one of the major disabling consequences in chronic kidney (CKD) disease which has different etiologies .Inadequate production of Erythropoietin (EPO) is the main cause of anemia. Iron shortage is the other important cause. The aim of this study is to evaluate Anemia Prevalence and iron storage in CKD patients in pre-dialysis and hemodialysis stages. Mater...
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عنوان ژورنال:
- Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
دوره 13 1 شماره
صفحات -
تاریخ انتشار 1998