EPB 41 L 3 ( erythrocyte membrane protein band 4 . 1 - like 3 )
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چکیده
منابع مشابه
Polyphenols Inhibit Band 3 Protein of the Erythrocyte Membrane
The effect of selected potential inhibitors of anion transport mediated by the Band 3 protein of the erythrocyte membrane was studied by the electron spin resonance (ESR) technique using Tempo-phosphate spin probe. No inhibition of Band 3-mediated transport by 1-cyano-4-hydroxycinnamic acid, inhibitor of monocarboxylate transporters (MCT) was found but inhibition by some polyphenols (curcumin >...
متن کاملLymphoma Thy-1 Glycoprotein Is Linked to the Cytoskeleton via a 4.l-like Protein
In this study we have found that the phosphoprotein doublet of 68,000 and 65,000 daltons (68/65 kD) in mouse T-lymphoma cells shares several structural and functional similarities with erythrocyte band 4.1. Our evidence for identifying the 68/65-kD doublet as a lymphoma 4.l-like protein is as follows: (a) it displays an immunological cross-reactivity with anti-erythrocyte band 4.1 antibody; (b)...
متن کاملAnion transport systems in the mouse erythrocyte: kinetic studies in situ and after expression of mouse erythroid band 3 protein in oocytes of Xenopus laevis.
The band 3 protein was first discovered in 1971 on SDS gel electropherograms of the human erythrocyte membrane, where it forms the third major band from the top [ 11. It is a glycoprotein with a molecular mass of about 100 kDa and consists of two domains of approximately equal size. One of them is hydrophobic and associated with the lipid bilayer. The other is hydrophilic and extends into the c...
متن کاملParticipation of caspase-3-like protease in oxidation-induced impairment of erythrocyte membrane properties.
Erythrocytes are very susceptible to oxidative stress, having a high content of intracellular oxygen and hemoglobin. In the present study, exposure to oxidative stress resulted in a significant impairment of erythrocyte membrane functions, such as deformability and anion exchange. Band 3 protein, also known as anion exchanger-1, plays an important role in these two functions. We show that oxida...
متن کاملRED CELLS Band 3 is an anchor protein and a target for SHP-2 tyrosine phosphatase in human erythrocytes
Tyr phosphorylation of the multifunctional transmembrane protein band 3 has been implicated in several erythrocyte functions and disorders. We previously demonstrated that pervanadate treatment of human erythrocytes induces band-3 Tyr phosphorylation, which is catalyzed by the sequential action of tyrosine kinase Syk and tyrosine kinase(s) belonging to the Src family. In this study, we show tha...
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تاریخ انتشار 2011