LinkedCT: A Linked Data Space for Clinical Trials

نویسندگان

  • Oktie Hassanzadeh
  • Anastasios Kementsietsidis
  • Lipyeow Lim
  • Renée J. Miller
  • Min Wang
چکیده

The Linked Clinical Trials (LinkedCT) project aims at publishing the first open semantic web data source for clinical trials data. The database exposed by LinkedCT is generated by (1) transforming existing data sources of clinical trials into RDF, and (2) discovering semantic links between the records in the trials data and several other data sources. In this paper, we discuss several challenges involved in these two steps and present the methodology used in LinkedCT to overcome these challenges. Our approach for semantic link discovery involves using state-of-the-art approximate string matching techniques combined with ontology-based semantic matching of the records, all performed in a declarative and easy-to-use framework. We present an evaluation of the performance of our proposed techniques in several link discovery scenarios in

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Automatic Curation of Clinical Trials Data in LinkedCT

The Linked Clinical Trials (LinkedCT) project started back in 2008 with the goal of providing a Linked Data source of clinical trials. The source of the data is from the XML data published on ClinicalTrials.gov, which is an international registry of clinical studies. Since the initial release, the LinkedCT project has gone through some major changes to both improve the quality of the data and i...

متن کامل

LinkedCT Live: Platform for Online Curation of Clinical Trials Data

The goal of the Linked Clinical Trials (LinkedCT) project is to transform the data published on ClinicalTrials.gov into a highquality knowledge base published as Linked Data on the Web. In this demonstration, we present the platform we have developed for both online curation of clinical trials data into linked data, and for rapid Web application development on top of this linked data. We also s...

متن کامل

Glocal Clinical Registries: Pacemaker Registry Design and Implementation for Global and Local Integration – Methodology and Case Study

BACKGROUND The ability to apply standard and interoperable solutions for implementing and managing medical registries as well as aggregate, reproduce, and access data sets from legacy formats and platforms to advanced standard formats and operating systems are crucial for both clinical healthcare and biomedical research settings. PURPOSE Our study describes a reproducible, highly scalable, st...

متن کامل

Characteristics of Clinical Trials in Iran: A Sample of 5000 Trials Registered in IRCT

Background and Objectives: A considerable number of clinical trials are conducted in Iran each year. Not much is known about the characteristics of them, this study aimed to investigate key characteristics of Iranian clinical trials.   Methods: All clinical trial protocols registered in IRCT until November 2013 were selected. Text mining techniques were used to extract information from data t...

متن کامل

Evidence Based Medicine and Herbal Medicine

  Evidence based medicine (EBM) can be found as far back as the 1940s. However, it was in 1972 that the concept first came into play, originated by Professor Archie Cochrane, in his book, Effectiveness & Efficiency: Random Reflections on Health Services. This was the foundation for evidence based research, and in 1992 a facility was funded by the UK government, with the aim of performing r...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • CoRR

دوره abs/0908.0567  شماره 

صفحات  -

تاریخ انتشار 2009