Neurobiology of Disease -Internexin Is Structurally and Functionally Associated with the Neurofilament Triplet Proteins in the Mature CNS

Aidong Yuan,1,3 Mala V. Rao,1,3 Takahiro Sasaki,1 Yuanxin Chen,1,2 Asok Kumar,1,3 Veeranna,1,3 Ronald K. H. Liem,5 Joel Eyer,6 Alan C. Peterson,7 Jean-Pierre Julien,8 and Ralph A. Nixon1,3,4 1Center for Dementia Research and 2Department of Medical Physics, Nathan Kline Institute, Orangeburg, New York 10962, Departments of 3Psychiatry and 4Cell Biology, New York University School of Medicine, New York, New York 10016, 5Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, 6Laboratoire Neurobiologie et Transgenese, Institut National de la Santé et de la Recherche Médicale, Centre Hospitalier Universitaire, 49033 Angers Cedex, France, 7Molecular Oncology Group, McGill University, Royal Victoria Hospital, Montreal, Québec, Canada H3A1A1, and 8Centre de Recherche du Centre Hospitalier de l’Université Laval, Département d’anatomie et Physiologie de l’Université Laval, Québec, Québec, Canada G1V 4G2