Hypophosphatemic Osteomalacia with Multiple Bone Fractures: ADV-Induced Fanconi's Syndrome
نویسندگان
چکیده
https://doi.org/10.4068/cmj.2018.54.1.78 C Chonnam Medical Journal, 2018 Chonnam Med J 2018;54:78-79 Corresponding Author: Kyung Ae Lee Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonbuk National University Medical School, 20 Geonji-ro, Deokji-gu, Jeonju 54907, Korea Tel: +82-63-250-2749, Fax: +82-63-254-1609, E-mail: [email protected] Article History: Received December 25, 2017 Revised January 1, 2018 Accepted January 6, 2018 FIG. 1. Coronal T1 weighted magnetic resonance imaging of both knees. Magnetic resonance imaging scans of both knee joints show incomplete nondisplaced microfractures across the femoral and tibial metaphyses. Hypophosphatemic Osteomalacia with Multiple Bone Fractures: ADV-Induced Fanconi’s Syndrome
منابع مشابه
Pathologic Femoral Neck Fracture Due to Fanconi Syndrome Induced by Adefovir Dipivoxil Therapy for Hepatitis B
In Fanconi syndrome, hypophosphatemic osteomalacia is caused by proximal renal tubule dysfunction which leads to impaired reabsorption of amino acids, glucose, urate, and phosphate. We present a rare case of a 43-year-old Korean male who was found to have insufficiency stress fracture of the femoral neck secondary to osteomalacia due to Fanconi syndrome. He had been receiving low-dose adefovir ...
متن کاملLong-term observation of osteomalacia caused by adefovir-induced Fanconi's syndrome.
A 64-year-old man suffering polyarthralgia and bone pain was referred to our hospital. Renal dysfunction, hypophosphatemia and increased levels of bone alkaline phosphatase were found. The patient's serum creatinine level had gradually increased after the initiation of adefovir dipivoxil administration for hepatitis B. In agreement with multifocal uptakes of bone scintigraphy, iliac bone biopsy...
متن کاملInsufficiency fractures related to low-dose adefovir dipivoxil treatment for chronic hepatitis B.
We present a case of a 53-year-old woman who developed multifocal insufficiency fractures associated with adefovir dipivoxil (ADV) induced osteomalacia, including recurring metatarsal insufficiency fractures and a subtrochanteric femoral insufficiency fracture requiring surgical fixation. She had received low-dose ADV treatment for 59 months for chronic hepatitis B viral infection at the time o...
متن کاملClinical features of hypophosphatemic osteomalacia induced by long-term low-dose adefovir dipivoxil
Objective To investigate the predictors of hypophosphatemic osteomalacia induced by adefovir dipivoxil (ADV) and to monitor for early detection. Patients and methods Hospitalized patients who were diagnosed with ADV-related hypo-phosphatemic osteomalacia were recruited and retrospectively analyzed in our hospital from January 2012 to December 2016. A telephone interview was conducted at 1, 3,...
متن کاملPathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report
UNLABELLED We present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia. He had a 13-month history of bone pain involving his shoulders, hips, and knee. He received adefovir dipivoxil for treatment of lamivudine-resistant hepatitis B virus infection for 5 years before the occ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 54 شماره
صفحات -
تاریخ انتشار 2018