Cinacalcet as first-line treatment for calciphylaxis.
نویسندگان
چکیده
منابع مشابه
Single base mutation in the fumarate hydratase gene leading to segmental cutaneous leiomyomatosis.
recently been drawn to the possible interest of einacalcet. a calcimimetic drug that increases the sensitivity of PTH-secreting cells to extracellular calcium, resulting in a decrease of PTH production. This molecule is currently routinely used in end-stage renal failureassociated secondary hyperparathyroidism (4) and its efficiency in calciphylaxis has already been reported in two patients, in...
متن کاملCinacalcet for the treatment of calciphylaxis.
Calciphylaxis is characterized by cutaneous ischemia and necrosis and is associated with a very high mortality rate. It usually affects patients who are undergoing dialysis or who have received a kidney transplant. There is no optimal treatment, but parathyroidectomy has shown some benefit. We report herein a case of a patient with calciphylaxis and secondary hyperparathyroidism who was success...
متن کاملRegression of vascular calcification following an acute episode of calciphylaxis: a case report
INTRODUCTION In clinical situations, vascular calcification tends to progress and is difficult to completely arrest or reverse. Calciphylaxis, a severe complication of end-stage renal disease, is a specific form of vascular calcification. Control studies have provided evidence that monotherapy with sodium thiosulfate or cinacalcet delays the progression of vascular calcification. Successful tre...
متن کاملCalciphylaxis in end-stage renal disease prior to dialytic treatment: a case report and literature review
INTRODUCTION Calciphylaxis is a rare medical condition that is usually diagnosed in patients suffering from end-stage renal disease who are already receiving renal replacement therapy and in those post-transplantation. The pathogenesis still remains to be fully elucidated; hence, the treatment is not uniform. The prognosis is generally poor. The ulcerative stage exhibits a worse prognosis than ...
متن کاملMulti-modal treatment of calciphylaxis with sodium-thiosulfate, cinacalcet and sevelamer including long-term data.
BACKGROUND Calciphylaxis is a rare, yet life-threatening disease mainly occurring in dialysis patients. Traditional options of treatment remain unsatisfactory. METHODS Here we present a novel, combined approach, treating calciphylaxis with IV sodium thiosulfate, cinacalcet and sevelamer. In a case series five hemodialysis patients, have been successfully treated with this regimen. Treatment a...
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عنوان ژورنال:
- Acta dermato-venereologica
دوره 88 1 شماره
صفحات -
تاریخ انتشار 2008