Tumor-infiltrating follicular helper T cells
نویسندگان
چکیده
By analyzing CD4+ lymphocytes in human breast carcinomas, we have recently uncovered the presence of follicular helper T cells in lesions exhibiting an extensive immune infiltrate. The presence of these specialized CD4+ T cells, which localize to the germinal centers of peritumoral tertiary lymphoid structures found in extensively infiltrated neoplastic lesions, predicts improved disease outcome among breast carcinoma patients.
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2013