Colonic Crypts: Safe Haven from Microbial Products
نویسنده
چکیده
The notion that the colon's deep crypt pockets provide a protected location that shields stem cells from potentially toxic substances is widely accepted. In this issue of Cell, Kaiko et al. reveal how a metabolite abundantly produced by the gut microbiota can inhibit stem cell proliferation but is blocked from doing so by crypt architecture.
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عنوان ژورنال:
- Cell
دوره 165 شماره
صفحات -
تاریخ انتشار 2016