Insulin Sensitivity Index in Young Healthy Danish Caucasians
نویسندگان
چکیده
Background. Insulin sensitivity and insulin secretion are traits that are both genetically and environmentally deter-
منابع مشابه
Analysis of the relationship between fasting serum uric acid and the insulin sensitivity index in a population-based sample of 380 young healthy Caucasians.
AIM To determine whether fasting serum uric acid is associated with the insulin sensitivity index or with other anthropometric, metabolic or environmental features of the insulin resistance syndrome in a population-based sample of young healthy Caucasians. METHODS The protocol included 380 unrelated Caucasian subjects (age 18-32 years) who had their insulin sensitivity index and glucose effec...
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OBJECTIVE Circulating leptin levels correlate positively with the degree of obesity and prolonged hyperinsulinaemia increases serum leptin levels. Moreover, insulin secreting beta-cells express functional leptin receptors indicating a functional relationship between leptin and insulin. The aim of this study was to examine the relationship between fasting serum leptin levels and measures of insu...
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The human plasma-cell membrane differentiation antigen-1 (PC-1) has been shown to inhibit insulin receptor tyrosine kinase activity. Recently, a K121Q polymorphism in the human PC-1 gene was found in a Sicilian population and was shown to be strongly associated with insulin resistance. The objectives of the present investigation were to examine in the Danish Caucasian population whether the K12...
متن کاملRelation between birth weight and the insulin sensitivity index in a population sample of 331 young, healthy Caucasians.
The objective was to study the association between birth weight and the insulin sensitivity index. Altogether, 331 unrelated Caucasian subjects aged 18-32 years with measures of the insulin sensitivity index and insulin secretion during a combined intravenous glucose and tolbutamide tolerance test were included in the study. The data on birth weight and length were obtained from the midwife rec...
متن کاملHigher insulin and glucagon-like peptide-1 (GLP-1) levels in healthy, young South Asians as compared to Caucasians during an oral glucose tolerance test.
OBJECTIVE Higher insulin levels during an oral glucose test (OGTT) have been shown in South Asians. We aimed to investigate if this increased insulin response causes reactive hypoglycemia later on, and if an increased glucagon-like-peptide-1 (GLP-1) response, which could contribute to the hyperinsulinemia, is present in this ethnic group. METHODS A prolonged, 6-h, 75-g OGTT was performed in h...
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تاریخ انتشار 2013