New Single-Cell Genome Amplification Method Aims to Reduce Biases to Detect Micro CNVs | GenomeWeb
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The researchers described the linear amplification via transposon insertion (LIANTI) method today in Science, reporting that it enables micro-copy number variation detection with kilobase resolution. Sunney Xie, senior author on the study, said that he is interested in using the method for preimplantation genetic screening and diagnosis, which typically rely on the analysis of single or very few cells to screen embryos for chromosomal alterations prior to implantation.
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تاریخ انتشار 2017