Evidence that in vitro adherence of Klebsiella pneumoniae to ciliated hamster tracheal cells is mediated by type 1 fimbriae.

نویسندگان

  • R C Fader
  • K Gondesen
  • B Tolley
  • D G Ritchie
  • P Moller
چکیده

Clinical isolates of fimbriated and nonfimbriated Klebsiella pneumoniae were examined for the ability to adhere to hamster tracheal cells cultured in vitro. Fimbriated-phase K. pneumoniae adhered preferentially to ciliated cells, whereas nonfimbriated-phase organisms were not adherent. The adherence was inhibited by D-mannose but not D-glucose, suggesting that type 1 fimbriae serve as the adhesin in the attachment process.

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عنوان ژورنال:
  • Infection and immunity

دوره 56 11  شماره 

صفحات  -

تاریخ انتشار 1988