Airway clearance techniques in cystic fibrosis: physiology, devices and the future.

نویسنده

  • Adrian H Kendrick
چکیده

The appearance of the lungs of a cystic fibrosis (CF) patient at post mortem is typically one of consolidation, with areas of bronchiectasis filled with mucopurulent material and of mucus plugging of the small airways (Yankaskas et al., 2004). The airways of the upper respiratory tract have increased secretion production, whilst in the lower respiratory tract there is increased mucus production and an increase in sputum. This sputum is usually thick and tenacious, becoming thicker and more abundant during an exacerbation and leading to progressive lung damage. It is therefore essential that in patients with CF the process of airway clearance is enhanced, where needed, to attempt to reduce these long-term effects.

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عنوان ژورنال:
  • Journal of the Royal Society of Medicine

دوره 100 Suppl 47  شماره 

صفحات  -

تاریخ انتشار 2007