Network-based drug-disease relation prioritization using ProphNet
نویسندگان
چکیده
Assisting drug repositioning processes can lead to a considerable reduction in cost and time in any drug development process. Recent in silico approaches have addressed the network-based nature of biological information to assess the possible new indications for a query drug. Here we present a new methodology based on network prioritization, that can aid researchers in the drug repositioning process by means of prioritizing drugs related to a query disease. Results show that selection of the data sources to be integrated can be a critical step towards success in drug repositioning.
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تاریخ انتشار 2013