Finding the Right Partner: Science or ART?
نویسندگان
چکیده
In response to environmental cues, certain plasma membrane proteins are ubiquitinated, signaling their endocytosis and degradation. In the budding yeast, a single enzyme, Rsp5, is charged with this task. Lin et al. (2008) now identify an arrestin-related family of Rsp5 adaptor proteins called ARTs that confer specificity on the ubiquitination of plasma membrane proteins and contribute to the maintenance of the correct cell surface protein repertoire.
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عنوان ژورنال:
- Cell
دوره 135 شماره
صفحات -
تاریخ انتشار 2008