FTO polymorphism (RS9939609) and BED in patients with morbid obesity for evaluation towards bariatric surgery

Background Obesity is a major health problem in the twenty-first century. Recent research shows that, among people with severe obesity, there is a sub-population that does not respond to behavioral treatment for weight loss. This group presents a type of eating disorder known as Binge Eating Disorder (BED). Recent studies indicate a link between obesity in adults and the rs9939609 polymorphism of the FTO gene. A frequent association of obesity and BED has also been found. Variations in the gene, including the rs9939609 polymorphism, have been associated with obesity and diabetes.