Individual Recognition: Mice, MUPs and the MHC
نویسنده
چکیده
Recognition requires that identity be assigned to specific individuals as a result of perceived differences in their unique features and attributes. A recent study demonstrates that this phenomenon occurs in mice, and reveals the genetic signal that underlies it.
منابع مشابه
The Genetic Basis of Individual-Recognition Signals in the Mouse
The major histocompatibility complex (MHC) is widely assumed to be a primary determinant of individual-recognition scents in many vertebrates [1-6], but there has been no functional test of this in animals with normal levels of genetic variation. Mice have evolved another polygenic and highly polymorphic set of proteins for scent communication, the major urinary proteins (MUPs) [7-12], which ma...
متن کاملMajor urinary protein (MUP) profiles show dynamic changes rather than individual “barcode” signatures
House mice (Mus musculus) produce a variable number of major urinary proteins (MUPs), and studies suggest that each individual produces a unique MUP profile that provides a distinctive odor signature controlling individual and kin recognition. This 'barcode hypothesis' requires that MUP urinary profiles show high individual variability within populations and also high individual consistency ove...
متن کاملDiversity of major urinary proteins (MUPs) in wild house mice
Major urinary proteins (MUPs) are often suggested to be highly polymorphic, and thereby provide unique chemical signatures used for individual and genetic kin recognition; however, studies on MUP variability have been lacking. We surveyed populations of wild house mice (Mus musculus musculus), and examined variation of MUP genes and proteins. We sequenced several Mup genes (9 to 11 loci) and un...
متن کاملThe ownership signature in mouse scent marks is involatile.
Male house mice advertise their territory ownership through urinary scent marks and use individual-specific patterns of major urinary proteins (MUPs) to discriminate between their own scent and that of other males. It is not clear whether recognition occurs through discrimination of the non-volatile proteins or protein-ligand complexes (direct model), or by the detection of volatile ligands tha...
متن کاملThe Direct Assessment of Genetic Heterozygosity through Scent in the Mouse
The role of individual genetic heterozygosity in mate choice is the subject of much current debate. Several recent studies have reported female preference for more heterozygous males, but the mechanisms underlying heterozygote preference remain largely unknown. Females could favor males that are more successful in intrasexual competition, but they could also assess male heterozygosity directly ...
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عنوان ژورنال:
- Current Biology
دوره 17 شماره
صفحات -
تاریخ انتشار 2007