Model of unequal chromosomal crossing over in DNA sequences

نویسندگان

  • Nikolay V. Dokholyan
  • Sergey V. Buldyrev
  • Shlomo Havlin
  • H. Eugene Stanley
چکیده

It is known that some dimeric tandem repeats (DTR) are very abundant in noncoding DNA. We nd that certain DTR length distribution functions in noncoding DNA can be t by a power law function. We analyze a simpli ed model of unequal chromosomal crossing over and nd that it produces a stable power law length distribution function, with the exponent = 2. Although the exponent predicted by this model di ers from those observed in nature, we argue that the biophysical process underlying this model provides the major contribution to the DTR length distribution function. c © 1998 Elsevier Science B.V. All rights reserved. PACS: 87.10.+e; 05.20.−y; 82.20.Hf

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تاریخ انتشار 1998