Gene-environment interplay.
نویسنده
چکیده
منابع مشابه
Gene-environment Interplay in Twin Models Gene-environment Interplay in Twin Models
In this article, we respond to Shultziner’s critique that argues identical twins are more alike not because of genetic similarity, but because they select into more similar environments and respond to stimuli in comparable ways, and these effects bias twin model estimates to such an extent that they are invalid. The essay further argues that the theory and methods that undergird twin models, as...
متن کاملGene-Environment Interplay in Twin Models
In this article, we respond to Shultziner's critique that argues that identical twins are more alike not because of genetic similarity, but because they select into more similar environments and respond to stimuli in comparable ways, and that these effects bias twin model estimates to such an extent that they are invalid. The essay further argues that the theory and methods that undergird twin ...
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Gene-environment interplay is a general term that covers several divergent concepts with different meanings and different implications. In this review, we evaluate research evidence on four varieties of gene-environment interplay. First, we consider epigenetic mechanisms by which environmental influences alter the effects of genes. Second, we focus on variations in heritability according to env...
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Although it is recognized that many common complex diseases are a result of multiple genetic and environmental risk factors, studies of gene-environment interaction remain a challenge and have had limited success to date. Given the current state-of-the-science, NIH sought input on ways to accelerate investigations of gene-environment interplay in health and disease by inviting experts from a va...
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For more than a decade, biometric moderation models have been used to examine whether genetic and environmental influences on individual differences might vary within the population. These quantitative gene X environment interaction (GxE) models not only have the potential to elucidate when genetic and environmental influences on a phenotype might differ, but why, as they provide an empirical t...
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عنوان ژورنال:
- Science
دوره 354 6308 شماره
صفحات -
تاریخ انتشار 2016