Polydopamine coated manganese oxide nanoparticles with ultrahigh relaxivity as nanotheranostic agents for magnetic resonance imaging guided synergetic chemo-/photothermal therapy† †Electronic supplementary information (ESI) available: Experimental procedures, supplementary figures and table of relaxivity of the present work and reported Mn-based nanoparticles. See DOI: 10.1039/c6sc01320a Click here for additional data file.

Polydopamine coated manganese oxide nanoparticles with ultrahigh relaxivity as nanotheranostic agents for magnetic resonance imaging guided synergetic chemo-/photothermal therapy.

Mn-based nanoparticles have been regarded as a new class of probes for magnetic resonance imaging (MRI), but their low relaxivity is the major obstacle for applications in vivo. Herein, we designed and constructed a multifunctional nanotheranostic (FA-Mn3O4@PDA@PEG) for MRI guided combinatorial chemo-/photothermal therapy (PTT) for cancer. The ultrahigh relaxivity of 14.47 mM-1 s-1 makes the na...

Design of an intelligent sub-50 nm nuclear-targeting nanotheranostic system for imaging guided intranuclear radiosensitization† †Electronic supplementary information (ESI) available: Experimental procedures, supplementary figures and preliminary evaluation of radiosensitization of MMC. See DOI: 10.1039/c4sc03080j Click here for additional data file.

A complex stereochemical relay approach to the antimalarial alkaloid ocimicide A1. Evidence for a structural revision† †Electronic supplementary information (ESI) available: Supplementary schemes, figures, and tables, general experimental remarks, synthetic procedures, catalogues of experimental and calculated nuclear magnetic resonance spectra. CCDC 1536046. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc01127j Click here for additional data file. Click here for additional data file.

Multifunctional mixed-metal nanoscale coordination polymers for triple-modality imaging-guided photodynamic therapy† †Electronic supplementary information (ESI) available: All experimental details, crystallographic data collection and refinement statistics, details of chemical synthesis, additional figures and tables. See DOI: 10.1039/c6sc05616d Click here for additional data file.

Self-quenched ferrocenyl diketopyrrolopyrrole organic nanoparticles with amplifying photothermal effect for cancer therapy† †Electronic supplementary information (ESI) available: Experimental methods and additional figures. See DOI: 10.1039/c7sc03351f Click here for additional data file.

Organic nanoparticles (NPs) with near-infrared absorbance possess high photothermal conversion (PTC) efficiency and an excellent photoacoustic signal, presenting a great prospect for photoacoustic imaging (PAI)-guided photothermal therapy (PTT). Herein, a novel diketopyrrolopyrrole derivative (DPPCN-Fc) is synthesized for use as a PTT agent with PAI performance. Due to photo-induced electron tr...