Antibody Humanization Techniques

Antibodies are proteins with very important functions in the immune system. Thanks to their ability to recognize specific sequences from pathogens and other threats, antibodies can participate in the recognition and removal of foreign threats, such as virus and bacteria (Janeway et al.). Every human body is able to create millions of slightly different antibodies; every antibody has the ability to recognize one specific foreign antigen (Greger & Windhorst, 2013). Antibodies are, therefore, highly specific, which makes them very useful in the biomedical research field and in applied medicine. Antibodies are crucial in several screening and diagnosis methods, and in the last couple of decades they have emerged as treatment option for several diseases, including arthritis, cardiovascular disease, transplant rejection and cancer (Gura, 2002).