Bromination and Dehydrobromination Studies on Some CIS-4a-Methyl-Decaline-2,7-Diones

Authors

  • K. Grohamann CUNY Graduate Center, Department of Chemistry, Hunter College, New York, N.Y. 10021, USA
  • L. Todaro Research Division, Hoffimann-La Roche, Inc., Nutly, NJ 07110, USA
  • Sasanin Karimi CUNY Graduate Center, Department of Chemistry, Hunter College, New York, N.Y. 10021, USA
Abstract:

Results of the bromination and dehydrobromination of several angular methylated decalindiones are described. The key reaction, base-induced cyclization of the monobromo keto ester (3), and the dibromo ketone (4), leads to the formation of tricyclic systems (6) and (9) respectively.

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Journal title

volume 13  issue 1

pages  13- 24

publication date 1994-06-01

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