Complications of patients with hematologic malignancies in a selected Iranian population

Authors

  • Ahmad Tamaddoni Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
  • farida abesi Dental Materials Research Center, Babol University of Medical Sciences, Babol, Iran
  • sorayya Khafri Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran
Abstract:

Background: Hematologic malignancies in childhood and their treatments can cause dental anomalies and jaw bone abnormalities; therefore, the aim of this study was to assess the prevalence of these disorders in children. Methods: This cross-sectional study was conducted on all children diagnosed with hematologic malignancies that referred to in Amirkola Children’s Hospital from 2011 to 2018. All of children underwent clinical evaluation in a Dental Radiology Clinic and panoramic imaging was performed. The radiographs were examined for dental anomalies and jaw bone abnormalities. The data were analyzed by descriptive analysis using chi-square, Mann-Whitney and Kruskal-Wallis with a 95% confidence interval. Results: The study population consisted of 32 children and 9.46% of these patients showed intraoral signs in clinical evaluations. Panoramic radiographs indicated dental anomalies in 12 (63.9%) and jaw bone abnormalities in 17 (89.4%) patients. The most common dental anomaly and bone abnormality were taurodontism and changes in lamina dura, respectively. By measuring the mandibular cortical index (MCI), it was revealed that 13 had osteopenia, in which 4 of them had severe osteopenia (osteoporosis). The statistical analysis demonstrated that there was a significant difference between the incidence of osteoporosis and changes in lamina dura with the gender (p<0.05). Conclusion: Due to early onset of osteopenia and osteoporosis and the presence of dental and bone abnormalities in half of study population, early assessment of their clinical and radiographic condition can be helpful in the prevention and the early treatment of their oral complications.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Fungal Infections in Pediatric Patients with Hematologic Malignancies

As the data on the epidemiology and outcome of fungal infections in children with hematologic cancer are limited especially in Iran, this study was aimed to delineate the epidemiologic features and outcome of fungal infections in this population. The medical records of all children with hematologic malignancies diagnosed with a fungal infection from 2005 to 2010 at a tertiary pediatric hospita...

full text

Cardiac operations in patients with hematologic malignancies.

OBJECTIVES Patients with hematologic malignancies are frequently in need of major cardiac operations. Previous reports suggest an increased risk for perioperative complications in these immunodeficient patients. METHODS Patients diagnosed with any type of hematologic malignancy who underwent open-heart surgery at our institution between 7/1996 and 6/2002 were identified. Their hospital charts...

full text

fungal infections in pediatric patients with hematologic malignancies

as the data on the epidemiology and outcome of fungal infections in children with hematologic cancer are limited especially in iran, this study was aimed to delineate the epidemiologic features and outcome of fungal infections in this population. the medical records of all children with hematologic malignancies diagnosed with a fungal infection from 2005 to 2010 at a tertiary pediatric hospital...

full text

Antifungal prophylaxis in patients with hematologic malignancies: a reappraisal.

F UNGAL INFECTIONS are an important cause of morbidity and mortality in patients with hematologic malignancies. Prolonged neutropenia, impaired cell-mediated immunity, and fungal colonization after the administration of broad-spectrum antibiotics are known predisposing fact o r ~ . “ ~ The risk of invasive fungal infection is particularly high in the setting of allogeneic bone marrow transplant...

full text

some specific chromosomal aberrations of hematologic malignancies in 80 iranian population

introduction: most of the hematologic malignancies are heterogenous with regard to morphology, immunophenotype, and genetic rearrangements. multiple recurrent chromosomal aberrations have been identified by conventional cytogenetic analysis, which is now widely recognized as one of the most important diagnostic and prognostic determinants in these patients. patients and methods: bone marrow sam...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 14  issue 1

pages  0- 2

publication date 2023-01

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023