Inspection of Digoxin level in cardiac heart failure patients refer to Taemin Ejtemai and Shohadaye Ashaer clinic

Authors

  • afshin Nazari
  • babak Bharvand
  • mehrdad Namdari
  • yaghob Sherkhani
Abstract:

Background: Heart failure is one of the common cardiovascular diseases and digoxin has the positive effect on it. But unfortunately in spite of its positive effect on heart failure therapeutic and toxic level of it in patients is different and close to each other. The aim of this research was determination of digoxin serum level in failur heart patients. Materials and methods: In this cross-sectional study 31 patients with heart failure and consumption digoxin refer to clinic were assessment. Some important factors including age, clearance creatinie, ejection fraction, urea, potassium, calsium and digoxin level were measured. Findings: The statistical analysis of data showed that there was a correlation (r=0.57, p<0.01) between age and digoxin level. Digoxin level correlated positively with serum urea (r=0.046, p<0.01) creatinine(r=0.049, p<0.01), and potassium(r=0.47, p<0.01). Conclusions: It was concluded that continues monitoring of digital level with due attention to creatinine clearance and measurement of digoxin level for prevent of digoxin toxicity was necessary was necessary to prevent digoxin toxicity.

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Journal title

volume 7  issue None

pages  43- 49

publication date 2006-01

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