Normal values of neutrophils/lymphocytes ratio, lymphocytes/monocytes ratio and platelets/lymphocytes ratio among Iranian population: Results of Tabari cohort

Authors

  • Agil Barzegar Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran
  • Amir Shamshirian Department of Medical Laboratory Sciences, Student Research Committee, School of Allied Medical Sciences, Mazandaran University of Medical Sciences, Sari, Iran
  • Iradj Maleki Gut and Liver Research Center, Mazandaran university of medical sciences, Sari, Iran
  • Mahmood Moosazadeh Health Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran
  • Motahareh Kheradmand Health Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran
  • Reza Alizadeh-Navaei Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran
Abstract:

Background: Neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) have a prognostic value in several types of diseases such as cancers and they vary in different races. So, we aimed to evaluate the normal range of these markers among healthy people to determine the normal value in Iranian population. Methods: In the present study, cross-sectional data of population-based cohort study named “Tabari cohort study” was utilized. In the first phase of Tabari cohort, 10255 participants aged 35-70 years from urban and rural areas of Sari, Mazandaran, Iran entered into the study. The study included a questionnaire survey and blood collection. Blood samples were collected after 12 hours fasting from all participants during the study. Hematological indices were measured for all samples using Celltac Alpha MEK-6510 K (Tokyo, Japan). Results: After sample exclusion, 2212 healthy subjects of Tabari's normal cohort population were investigated. The mean age of the samples was 47.9±9.29 years. The mean of NLR, LMR, PLR were 1.70±0.70, 11.15±3.14 and 117.05±47.73, respectively. Conclusion: Our investigation provides preliminary reference values for NLR, LMR, and PMR among Iranian population that can be used for disease progress in various clinical procedures.

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Journal title

volume 10  issue 3

pages  320- 325

publication date 2019-06

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