Supplementation with omega-3 plus vitamin E and zinc plus vitamin C on metabolic syndrome components in postmenopausal women with type 2 diabetes

Authors

  • Masoud Kimiagar Human Nutrition & Diet Therapy Department, School of Nutrition and Food Technology, Shaheed Beheshti University of Medical Sciences. Tehran, Iran
  • Mohammad Reza Mahmoodi Physiology Research Center, Institute of Basic and Clinical Physiology & Nutrition Department, School of Health, Kerman University of Medical Sciences. Kerman, Iran
  • Yadollah Mehrabi Department of Health and Social Medicine, School of Medicine, Shaheed Beheshti University of Medical Sciences. Tehran, Iran
Abstract:

Background: The aim of this study was to find the influence of supplementation with omega-3 plus vitamin E and vitamin C plus zinc on metabolic syndrome components. Methods: In a double-blind controlled clinical trial, 75 diabetic postmenopausal women were randomly assigned to one of the three therapeutic groups of daily supplementation of 1.8g omega-3 plus 400mg vitamin E (group A), 5mg zinc plus 300mg vitamin C (group B), or placebo (group C) for 12 weeks and the results were evaluated. Results: One-way repeated measures ANOVA showed that systolic and diastolic blood pressure and waist circumference showed significant difference before and after the intervention (P= 0.0001, 0.001, and 0.045, respectively). Results of Univariate ANOVA showed that the level of plasma fasting blood sugar (FBS) and HDL-cholesterol significantly increased (P=0.01 and P=0.03, respectively) in patients who had been diagnosed as diabetic ≤7 years in group B. The plasma TG concentration significantly decreased (P=0.007) in patients who had been diagnosed as diabetic ≤7 years in group A. Systolic and diastolic BP significantly decreased (P=0.005 and P=0.04, respectively) in patients who had been diagnosed as diabetic ≤7 years in group A. The most effectiveness of nutraceutical supplementation was on patients that had been diagnosed as diabetic ≤7 years. Plasma TG and systolic BP decreased with omega-3 plus vitamin E; however, plasma FBS and HDL- cholesterol increased with zinc plus vitamin C supplementation. Conclusion: Several factors, such as duration of diabetes, age, gender, pathophysiology status, genetic, and other anthropometric characteristics may influence the effectiveness of supplementation.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Vitamin D Deficiency is Associated with the Metabolic Syndrome in Subjects with Type 2 Diabetes

Background and Objectives: There is convincing evidence that subjects concomitantly affected by type 2 diabetes (T2D) and metabolic syndrome (MeS) are at greater risk for cardiovascular disease (CVD). Many metabolic derangements in T2D might be attributed to poor vitamin D status. The purpose of this study was to investigate the associations among vitamin D status, MeS and glycemic status in su...

full text

vitamin d deficiency is associated with the metabolic syndrome in subjects with type 2 diabetes

background and objectives: there is convincing evidence that subjects concomitantly affected by type 2 diabetes (t2d) and metabolic syndrome (mes) are at greater risk for cardiovascular disease (cvd). many metabolic derangements in t2d might be attributed to poor vitamin d status. the purpose of this study was to investigate the associations among vitamin d status, mes and glycemic status in su...

full text

various effects of omega 3 and omega 3 plus vitamin e supplementations on serum glucose level and insulin resistance in patients with coronary artery disease

background: omega 3 and vitamin e are two critical nutrients which include beneficial effects in coronary artery disease (cad). the aim of this study was to assess the effects of omega 3 alone supplementation or in combination with vitamin e on serum glucose and lipid levels and insulin resistance in cad patients. methods: participants of this clinical trial included 60 male patients with cad w...

full text

Osteoporosis and Osteoporotic Fractures in Postmenopausal Women with Type 2 Diabetes Compared with Non-Diabetic Cases

Objective: Correlation of osteoporosis (OP) with type 2diabetes mellitus (DM) , is not as clear as type 1 DM. The purpose of this study was to compare the frequency of OP and osteoporotic fractures in post- menopausal women with and without type 2 DM in Sari, Iran. Materials and Methods: Eighty post-menopausal women with type 2 DM and 80 non-diabetic controls enrolled in this study. Bone mine...

full text

Effect of Vitamin E and omega 3 fatty acids in type 2 diabetes mellitus patients

Diabetes mellitus (DM) and its complications have been implicated in hyperglycemia-induced oxidative stress. Antioxidants can improve glycemic control, lipid profile, and cognitive functions. We assessed the effect of Vitamin E and omega 3 fatty acids (OFA) on the above parameters. One hundred patients with type 2 DM receiving metformin 500 mg and glimepiride 1 mg were randomized to receive add...

full text

Protective effects of omega-3, atorvastatin, vitamin E and vitamin C against doxorubicin-induced cardiotoxicity in rats: a comparison study

Introduction: The stress-oxidative is involved in doxorubicin (DOX)-induced cardiotoxicity. Due to the potential and previous reported for antioxidant properties of atorvastatin, omega-3, vitamin E and vitamin C, their efficacy to prevention of DOX-induced cardiotoxicity was investigated in this study. Methods: Fifty-six male rats were divided into 8 groups which received omega-3, atorvastati...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 26  issue 1

pages  43- 54

publication date 2019-01-01

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023