Reza Ghaffarzadegan
Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, I.R. IRAN
[ 1 ] - Optimization of the Glycyrrhizic Acid Extraction from Licorice by Response Surface Methodology
This study aims to extract Glycyrrhizic Acid (GA) from Glycyrrhiza glabra L. (licorice) using a novel, high efficiency, and low-cost extraction method. Water was chosen as the proper solvent for the extraction process to eliminate the requirement of harmful and toxic solvents, prepare an environmentally friendly process, and reduce the costs. The effect of differe...
[ 2 ] - Optimization of Atropine Extraction Process from Atropa Belladonna by Modified Bubble Column Extractor with Ultrasonic Bath
Modified Bubble Column Extraction with Ultrasonic Bath (BCE-UB) method was used to extract atropine from the stem and leaves of Atropa belladonna. Optimum condition were obtained with Kamada solvent which was chloroform-methanol-ammonia 15:15:1(v/v/v) as extraction solvent, the particle size of less than 350 µm, an extraction time of 23.95 min, a liquor to material ratio of 15.08 mL/g and...
[ 3 ] - Optimal Fabrication of Nano Menthol/PEG Particles by Electrospraying
Background: L-menthol [(1R,3R,4S)-(-)-menthol] is a flavoring that is the main component of mint herb essential oils, especially of the Mentha piperita and Mentha arvensis species. Its low solubility in aqueous systems makes precise formulation necessary in the final products. Of the methods available for fabrication of nanoparticles for use in pharmaceuticals, electrospraying is easy and requi...
[ 4 ] - Antibacterial and Wound Healing Properties of Thymol (Thymus vulgaris Oil) and its Application in a Novel Wound Dressing
Background: In developing new products for skin care and wound treatment, biocompatibility plays a major role in the choice of ingredients. Thymol, an essential oil extracted from thyme plant, exhibits outstanding antibacterial properties, but more importantly, it proves to be much more compatible to skin cells in comparison to some conventionally used antibiotic drugs and chemicals. Objectiv...
[ 5 ] - Study of Hypoglycemic Effect of Juglans regia Leaves and its Mechanism
Background: Hypoglycemic effect of Juglans regia leaves was reported in other previous researches. Objective: To investigate the mechanism of hypoglycemic action of Julans regia Leaves Methanolic Extract (JRLME), we designed the following study. Methods: Male wistar rats were classified in five groups, each of six, including alloxan-induced diabetic rats treated with JRLME at doses of 250...
[ 6 ] - تغلیظ عصاره بابونه آلمانی (Matricaria chamomilla) به وسیله غشای نانو فیلتراسیون
گیاه بابونه از سالیان دور به علت داشتن مواد مؤثره مفید برای انسان در مصرف های دارویی، غذایی و آرایشی و بهداشتی استفاده می‌شود .هدف از تغلیظ عصاره بابونه به وسیله غشای نانو فیلتراسیون استفاده از روشی ساده، ارزان، با گزینش بهتر و بازدهی بالاتر و هم‌چنین خودکارسازی آسان، مقیاس و زمان فرایند کوتاه‌تر، هزینه‌های پایین‌تر و شرایط بهره‌برداری بهتر است. در این پژوهش تغلیظ عصاره بابونه به روش غشا...
[ 7 ] - Statistical Optimization of Production Conditions of Polycaprolactone-Chitosan-Curcumin Particles
Curcumin is an herbal plant with great therapeutic applications. Although it is useful in treating several diseases, its low solubility in water and low bioavailability in living systems are limiting factors in using curcumin as a medicine. One way to overcome these shortcomings is the production of curcumin micro/nano particles. In this research, the particles of curcumin loaded with polycapro...