آزادبخت, محمد

[ 1 ] - شیرخشت در طب سنتی ایران و منابع جدید

سابقه و هدف: طب سنتی ایران که بخشی از میراث علمی و تاریخی کشورمان است دارای دستورات و تدابیر خاص است که نشان می­دهد ایرانیان نه تنها در زمان‌های گذشته از پایه‌گذاران  دانش پزشکی بوده­اند، بلکه پس از ظهور اسلام و در جریان شکل­گیری تمدن اسلامی نقش مهمی در رشد دانش پزشکی داشته­اند. در این میان انتقال علمی یافته­­های طب سنتی به طب نوین در فرآیندی کاملاً علمی تجربی از وظایف  بسیار خطیری است که به عهد...

[ 2 ] - "ماءالجبن" دارویی در طب سنتی ایران

Background and purpose: In Iranian Traditional Medicine (ITM), human body is composed of substances called humors. Any change in quantity or/and quality of these humors causes many diseases and their treatment requires purgation of pathogenic substances. Among the drugs introduced in ITM, ‘Maoljobon’ is considered with wide uses. This drug with nutritional benefits is used both alon...

[ 3 ] - ضرورت استاندارد کردن عصاره گیاهان دارویی در تحقیقات و نحوه انجام آن

Background: Over 80% of the world population depends on herbal medicines and products for healthy living, and also, around 80% of all pharmaceutical materials are derived directly or indirectly from plant sources. So, there is increasing general acceptability of the use of medicinal plants in today’s medical sciences researches. Plants are valuable for modern medicine in four basic ways; ...

[ 4 ] - Antidepressant Effect of Asperugo procumbens L. in Comparison with Fluoxetine: a Randomized Double Blind Clinical Trial

Background and objectives: Aseprugo procumbens is used as antianxety and depression in Iranian traditional medicine; however no clinical trial has been performed about these properties. The aim of this study was to evaluate the antidepressant efficacy and safety of hydroalcoholic extract of A. procumbens. Methods: In this double blind study, 3...

[ 5 ] - Optimization of Ultrasound-assisted Acidic-solvent Extraction of Colchicine from Colchicum kurdicum (Bornm.) Stef. Using Response Surface Methodology

Background and objectives: Colchicum kurdicum (Bornm.) Stef. is a flowering perennial monocotyledon plant that has many important bioactive compounds especially colchicine and colchicine derivatives. In this study, the ultrasound-assisted acidic-solvent extraction method coupled with response-surface method was presented as the successful method for large scale extract...

[ 6 ] - Evaluation of therapeutic strategies of neonatal jaundice by medicinal herbalists of Mazandaran province: a descriptive cross sectional study

Background: Neonatal jaundice is as a disease caused by the abnormality of bilirubin metabolism that tendency of people to traditional medicine is very high for the treatment. Objective: The aim of this study was to determine the therapeutic strategies, especially herbal treatments, in the neonatal jaundice, for mother and infant, based on verbally traditional medicine recommended by medicinal ...

[ 7 ] - A Mini-Review on Iron Chelating Agents as a Promising Therapeutic Target in Treatment of Leishmaniasis

There is a high prevalence of infections caused by Leishmania parasites and increasing rate of drug resistance. Lack of successful treatment with existing drugs calls for new therapeutic approaches. The main strategy in treatment of leishmaniasis is creating apoptosis and eliminating different forms of the parasite. So far, numerous drugs with specific mechanisms including 14-α-demethylase enzy...

[ 8 ] - Optimization of Colchicine Extraction from Colchicum Kurdicum (Bornm.) Stef. Corm and Evaluating Anti-Inflammatory and Anti-Oxidant Activities of the Plant Extract

Background and purpose: Colchicum kurdicum (Bornm.) Stef. is a monocotyledon plant which is endemic to Iran. The corm and seeds of this plant have some bioactive compounds, especially tropolone alkaloids that are used in treatment of inflammations, rheumatoid arthritis, gout, joint pains, and cancers. This study aimed at optimization of colchicine extraction from the corms of C. kurdicum and ev...

[ 9 ] - Antibacterial Activities of Gel Containing 5% Hydroalcoholic Extract of Rhamnus cathartica L. bark

Background and purpose: Acne is a chronic inflammatory disease of the pilosebaceous glands caused by opportunistic microorganisms. The Rhamnus cathartica is known to have biological and antioxidant properties. This research aimed at investigating the in vitro effect of gel containing 5% R. cathartica extract on acne vulgaris. Materials and methods: The gel formulation contained 25g of dried R...

[ 10 ] - Formulation, Preparation and Evaluation of Antiperspirant Effects of Hydrogel of Salvia virgata Jacq Aerial Part: A Randomized, Double Blind and Placebo-Controlled Clinical Trial

Background and purpose: Salvia virgata Jacq has antioxidant, antibacterial, anti-inflammatory, antinociceptive, antispasmodic, and healing effects. The aim of this study was to prepare and antiperspirant clinical evaluation of aerial gel formulation of this plant. Materials and methods: The aerial parts of the plant were collected from Hezarjarib forest in Mazandaran, spring 2017. The samples ...

[ 11 ] - Efficacy of a Gel from the Seed of Trigonella foenum-graceum L. in Preventing Trichoptilosis: A Randomized Placebo-Controlled Clinical Trial

 Background and purpose: Trichoptilosis with fragility and hair loss is a common disorder, but, still there is no specific and effective treatment for this condition. The aim of this study was to evaluate the efficacy of gel from the seed of Trigonella foenum-graceum L. in prevention of trichoptilosis in people with trichoptilosis. Materials and methods: A double-blind placebo controlled clini...

[ 12 ] - Evaluating the Effect of Lipogel Formula Containing Extracts of Rhamnus cathartica L. on Wound Healing in Wistar Rats

Background and purpose: Wound is a complication that is highly prevalent. The aim of this study was to investigate the effect of a lipogel formulation containing Rhamnus cathartica L., a native Iranian plant, on wound healing in Wistar rats. Materials and methods: In this experimental study, to find the best lipogel formula, several formulations with different ratios of paraffin, polyethylene ...