Ali Davoodi
Department of Pharmacognosy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran. Medicinal Plants Research Center, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran.
[ 1 ] - Materia Medica Used in Jaundice Based on Persian Medicine
Jaundice is recognized by increased bilirubin level of blood and yellow appearance in skin, sclera and mucous membrane. Natural products have been used for treatment of jaundice for a long time and Persian Medicine can be a good source of natural drugs for this purpose. This study was done to find the materia medica used for jaundice based on Persian medicine (PM) texts including The Canon of Med…
[ 2 ] - Starting Dose Calculation for Medicinal Plants in Animal Studies; Recommendation of a Simple and Reliable Method
Background and purpose: Research studies indicate that almost 80% of the present day drugs are derived directly or indirectly from medicinal plants. The estimation of a safe starting dose is a concern when a new substance is to be investigated including medicinal plants, in clinical and laboratory studies. This study was intended to explore a simple and reliable method of calcula…
[ 3 ] - بررسی اثرات ضد سرطانی سنه سیونین و پیرگیاه در رده های سلولی سرطانی پروستات
Background and purpose: This research aimed at evaluating the effects of senecionine and Senecio vulgaris extract on apoptosis and cell cycle inhibition. Also, their cytotoxicity on prostate cancer cell lines (PC3, DU145 and HGFs), antioxidant effects, and influences on AR and CLU gene expression were investigated. Materials and methods: In this experimental study, senecionine and S. vulgaris ex…
[ 4 ] - Plant cells technology as an effective biotechnological approach for high scale production of pharmaceutical natural compounds; A meta-analysis study
Natural-based drugs are the important bioactive substances that have been used for prevention and treatment of diseases. Natural products should be prepared in commercial scale from relevant medicinal plants. Hence, large amounts of the plants have been needed for extraction and isolation of compounds of natural origin. Plant cells technology is the best strategy for the production of the plant-d…
[ 5 ] - بررسی اتنوبوتانیک گیاهان دارویی مورد استفاده در بیماری‌های پوستی در منطقه اَلَموت قزوین
مقدمه: از دیرباز تاکنون گیاهان دارویی به صورت خودرو یا کاشته شده به‌عنوان منبع دارویی مهمی مورد استفاده‌ی بشر و حتی جانوران قرار می‌گرفته‌اند. گیاه‌شناسی سنتی روش‌های ارزشمندی را برای یافتن گیاهان دارویی جدید و داروهای گیاهی عرضه می‌کند. هدف: هدف از این مطالعه شناسایی گیاهان دارویی بومی و غیربومی مهمی است که به‌طور گسترده بوسیله‌ی ساکنان محلی، در درمان بیماری‌های پوستی در منطقه‌ی اَلَموت قزوین مورد…
[ 6 ] - Effect of Prunus Mahaleb L. Seed Extract on Ethylene glycol- and Ammonium Chloride-Induced Urolithiasis in BALB/c Mice
Background: Kidney stone disease can be quite painful, recurrent, and affects many people. Despite advances in drug therapy, there is still a need to find effective drugs with fewer complications for long-term treatment of kidney stones and to prevent its recurrence. The present study aimed to evaluate the effect of Prunus mahaleb L. seed extract on ethylene glycol- and ammonium chloride-induced …
[ 7 ] - Optimization of Ultrasound-assisted Acidic-solvent Extraction of Colchicine from Colchicum kurdicum (Bornm.) Stef. Using Response Surface Methodology
Background and objectives: Colchicum kurdicum (Bornm.) Stef. is a flowering perennial monocotyledon plant that has many important bioactive compounds especially colchicine and colchicine derivatives. In this study, the ultrasound-assisted acidic-solvent extraction method coupled with response-surface method was presented as the successful method for large scale extractio…
[ 8 ] - راهکارهای درمانی بیماری زردی نوزادان توسط عطاری‌های استان مازندران: یک مطالعه مقطعی توصیفی
مقدمه: زردی نوزادان، یک بیماری ناشی از عدم متابولیسم طبیعی بیلی روبین است که جهت درمان آن مردم به طب سنتی گرایش بسیار زیادی دارند. هدف: هدف از این بررسی راهکارهای درمانی بخصوص درمان‌های گیاهی، مؤثر در درمان زردی نوزادان به صورت تفکیک شده برای مادر و نوزاد بر مبنای طب سنتی شفاهی نقل شده توسط عطاران در استان مازندران می‌باشد. روش بررسی: این مطالعه مقطعی توصیفی در سال 1394 بر روی کلیه‌ی عطاران استان…
[ 9 ] - A Mini-Review on Iron Chelating Agents as a Promising Therapeutic Target in Treatment of Leishmaniasis
There is a high prevalence of infections caused by Leishmania parasites and increasing rate of drug resistance. Lack of successful treatment with existing drugs calls for new therapeutic approaches. The main strategy in treatment of leishmaniasis is creating apoptosis and eliminating different forms of the parasite. So far, numerous drugs with specific mechanisms including 14-α-demethylase enzyme…
[ 10 ] - Optimization of Colchicine Extraction from Colchicum Kurdicum (Bornm.) Stef. Corm and Evaluating Anti-Inflammatory and Anti-Oxidant Activities of the Plant Extract
Background and purpose: Colchicum kurdicum (Bornm.) Stef. is a monocotyledon plant which is endemic to Iran. The corm and seeds of this plant have some bioactive compounds, especially tropolone alkaloids that are used in treatment of inflammations, rheumatoid arthritis, gout, joint pains, and cancers. This study aimed at optimization of colchicine extraction from the corms of C. kurdicum and eval…
[ 11 ] - Protective Effect of Sankol Herbal Product on Kidney Stone in Balb/C Mice
Background and purpose: Kidney stone is a common form of kidney disease and many efforts have been made to find medications for its prevention and treatment. Current study evaluated the protective effects of Sankol herbal product in the formation of renal stone in male Balb/c mice. Materials and methods: Nephrolithiasis was induced in male Balb/C mice within 21 days by adding 75% ethylene glycol…
[ 12 ] - Antibacterial Activities of Gel Containing 5% Hydroalcoholic Extract of Rhamnus cathartica L. bark
Background and purpose: Acne is a chronic inflammatory disease of the pilosebaceous glands caused by opportunistic microorganisms. The Rhamnus cathartica is known to have biological and antioxidant properties. This research aimed at investigating the in vitro effect of gel containing 5% R. cathartica extract on acne vulgaris. Materials and methods: The gel formulation contained 25g of dried R. …
[ 13 ] - Response Surface Methodology for Optimization of Supercritical Fluid Extraction of Orange Peel Essential Oil
Background: Orange peel essential oils were obtained using supercritical fluid extraction. This method is an important high scaling extraction method used for the extraction of plant and animal extracts. Objectives: The aim of this study was the optimization of the extraction of the orange peel essential oil. Methods: The experimental parameters of Supercritical Fluid Extraction (SFE) such as tem…
[ 14 ] - Formulation, Preparation and Evaluation of Antiperspirant Effects of Hydrogel of Salvia virgata Jacq Aerial Part: A Randomized, Double Blind and Placebo-Controlled Clinical Trial
Background and purpose: Salvia virgata Jacq has antioxidant, antibacterial, anti-inflammatory, antinociceptive, antispasmodic, and healing effects. The aim of this study was to prepare and antiperspirant clinical evaluation of aerial gel formulation of this plant. Materials and methods: The aerial parts of the plant were collected from Hezarjarib forest in Mazandaran, spring 2017. The samples we…
[ 15 ] - Effect of Lipogel Containing Extracts of Eryngium campestre L. and Satureja hortensis L. on Wound Healing in Male Wistar Rats
Background and purpose: Wound is a type of injury with high prevalence in the society. The main requirement for wound management is rapid and complete wound healing without the spread of infection. Medicinal plants are affordable and accessible and suggested as one of the key treatment options. The aim of this study was to investigate the effect of lipogel formulations containing the extracts …
[ 16 ] - Antimicrobial and Synergistic Effects of Garlic and Cinnamon Extract Compared with Fluoride Varnish on Oral Lactobacillus acidophilus and Streptococcus mutans in Laboratory Conditions
Background and purpose: Garlic and cinnamon extracts, like fluoride varnish, play a role in caries control due to their antimicrobial effect and controlling demineralization. This analytical laboratory study was conducted in 2021 to investigate the antimicrobial effect of garlic and cinnamon extracts compared with fluoride varnish in controlling the infection of oral Lactobacillus acidophilus and…
Co-Authors