رستمی نژاد, محمد

دکترای ایمنی شناسی بالینی، مرکز تحقیقات بیماری های کبد و گوارش، دانشگاه علوم پزشکی شهید بهشتی

[ 1 ] - ارزیابی وضعیت کیست هیداتید در دام های کشتار شده استان اصفهان

سابقه و هدف: بیماری کیست هیداتید ناشی ازمرحله لاروی اکینوکوکوس گرانولوزوس بوده که هنوز هم یکی از عوامل مهم ایجاد کننده معضلات اقتصادی و بهداشتی در نواحی مختلف جهان است. هدف از انجام این مطالعه بررسی میزان شیوع کیست هیداتید در دام‌های کشتار شده در کشتارگاه های استان اصفهان بود. روش بررسی: در این مطالعه آخرین وضعیت آلودگی کیست هیداتید در استان اصفهان روی 4062 راس گوسفند، بز و گاو که از بهمن 139...

[ 2 ] - شیوع بیماری سیلیاک و توکسو پلاسموزیس در دوران حاملگی

سابقه و هدف: بیماری سیلیاک یک نقص خود ایمنی است که با حساسیت به گلوتن همراه بوده و در افراد مستعد از لحاظ ژنتیکی دیده می‌شود. با توجه به اینکه درباره بیماری سیلیاک و عفونت توکسوپلاسما گوندی و نیز ارزیابی ارتباط این دو در حاملگی هیچ گزارشی در دست نمی باشد، هدف این مطالعه تخمین شیوع سیلیاک تشخیص داده نشده و عفونت توکسوپلا سما گوندی در زنان حامله می باشد. روش بررسی: در این مطالعه توصیفی طی سال 1...

[ 3 ] - شیوع بیماری سیلیاک در مبتلایان به سوء‌ هاضمه

  سابقه و هدف: سوءهاضمه در افراد می‌تواند نشانه غیر اختصاصی بیماری سیلیاک باشد و غربال‌گری این بیماران شاید بتواند به تشخیص اولیه افراد مبتلا کمک کند. هدف این مطالعه تعیین شیوع بیماری سیلیاک در بیماران مبتلا به سوءهاضمه است که به‌صورت روتین جهت تشخیص مورد آندوسکوپی قسمت فوقانی معده-روده‌ای قرار گرفته‌اند.   مواد و روش ‌ ها: بین سال‌های 87-86، 407 بیمار که به دلایل مختلف آندوسکوپی شده بودند (193...

[ 4 ] - Introducing Transthyretin as a Differentially Expressed Protein in Washing Subtype of Obsessive-Compulsive Disorder

Introduction: Obsessive-Compulsive Disorder (OCD) as one of the important mental problems is valuable topic for proteomic research studies to better understand the underlying mechanisms of this disorder.  Methods: In this paper, gel-based proteomic was used to investigate the proteome profile of 16 female patients with OCD, washing subtype before and after treatment with fluoxetine and co...

[ 5 ] - Proteomics Applications in Health: Biomarker and Drug Discovery and Food Industry

Advancing in genome sequencing has greatly propelled the understanding of the living world, however, it is insufficient for full description of a biological system. Focusing on, proteomics has emerged as another large-scale platform for improving the understanding of biology. Proteomic experiments can be used for different aspects of clinical and health sciences such as food technology, biomark...

[ 6 ] - Proteomics Applications in Health: Biomarker and Drug Discovery and Food Industry

Advancing in genome sequencing has greatly propelled the understanding of the living world, however, it is insufficient for full description of a biological system. Focusing on, proteomics has emerged as another large-scale platform for improving the understanding of biology. Proteomic experiments can be used for different aspects of clinical and health sciences such as food technology, biomark...

[ 7 ] - بررسی اختلالات تغیرات بیان ژن Lnc13 در بیماران مبتلا به سلیاک در مقایسه با افراد سالم و همبستگی با ویژگی های کلینیکوپاتولوژیک

مقدمه بیماری سلیاک نوعی بیماری خود ایمنی بوده که در آن فرد، با مصرف گلوتن موجود در گندم، جو و چاودار دچار نوعی پاسخ ایمنی گشته، که در نهایت منجر به از بین رفتن پرزهای روده‌‌ باریک می‌‌شود. با توجه به نقش محرز ژن‌‌های غیر کدکننده در بیماری سلیاک و تاثیر آنها در پیشرفت بیماری، این مطالعه جهت بررسی بیان ژن Lnc13 در بیماران مبتلا به سلیاک در مقایسه با گروه کنترل طراحی شد. مواد و روش‌‌ها مطالعه حاضر...

[ 8 ] - An Overview on Probiotics as an Alternative Strategy for Prevention and Treatment of Human Diseases

Aims: Probiotics are viable and useful microorganisms, which are beneficial factors for human and animal health by altering their microbial flora. Most of the probiotics belong to a large group of bacteria in the human gastrointestinal tract. There are several clinical shreds of evidence that show anti-carcinogenic effects of probiotics through altering digestive enzymes, inhibition of carcinog...

[ 9 ] - Pharmaceutical Advances and Proteomics Researches

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

[ 10 ] - An Overview on Probiotics as an Alternative Strategy for Prevention and Treatment of Human Diseases

Aims: Probiotics are viable and useful microorganisms, which are beneficial factors for human and animal health by altering their microbial flora. Most of the probiotics belong to a large group of bacteria in the human gastrointestinal tract. There are several clinical shreds of evidence that show anti-carcinogenic effects of probiotics through altering digestive enzymes, inhibition of carcinog...

[ 11 ] - Pharmaceutical Advances and Proteomics Researches

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

[ 12 ] - Assessment of Saffron Neuroprotective Properties in Rat Retina versus Light Damage

Background and objectives: Crocus sativus L. (Iridaceae) commonly known as saffron, is a popular spice which is used for its pleasant aroma and favored color. Regarding the previous reports about the neuroprotective be...

[ 13 ] - Weak Anti-inflammatory and Anti-cancer Properties of Saffron

Background and objectives: Positive role of saffron in human health promotion has been investigated in widespread researches. Anticancer property, neuroprotection, protection of cardiovascular system and several positive properties are reported for saffron customers. The aim of this study was assessment of saffron weakness against light damage in rat retina. Methods:</s...

[ 14 ] - Evaluation of Anticancer and Neuroprotective Properties of Curcumin: a Network Analysis

Background and objectives: Curcumin as a medicinal substance has shown effective in different kinds of diseases especially cancer. To understand its underlying mechanism, molecular complementary study of differentially expressed microRNAs (DEMs) could assist. In this view, regulatory network analysis of DEMs of melanoma cancer treated with curcumin versus the untreated male <em...

[ 15 ] - Bioinformatics Investigation and Contribution of Other Chromosomes Besides Chromosome 21 in the Risk of Down Syndrome Development

Introduction: Down syndrome as a genetic disorder is a popular research topic in molecular studies. One way to study Down syndrome is via bioinformatics.  Methods: In this study, a gene expression profile from a microarray study was selected for more investigation. Results: The study of Down syndrome patients shows specific genes with differential expression and network centrality properties....

[ 16 ] - Comparison of the Lactobacillus and Bifidobacterium Population in Fecal Microbiome of Celiac Disease Patients on Gluten-Free Diet With Healthy Subjects

Aims Celiac disease (CD) is a chronic autoimmune disease triggered by gluten and other environmental factors, such as intestinal microbiota in genetically predisposed persons. This study aimed to evaluate the composition of the target gut microbiota population in patients with CD and to compare it with healthy individuals. Methods & Materials In this case-control study, Bifidobacterium and Lac...