Mohammad Hayatbakhsh

Gastroenterology and Hepatology Research Center, Kerman University of Medical Sciences, Kerman, Iran

[ 1 ] - Effect of Apium graveolens and Trachyspermum copticom on clinical symptoms of patients with functional dyspepsia

Objectives:This study aimed at investigating the effect of Iranian traditional remedy prepared from Apium graveolens and Trachyspermum copticom (AT) on the severity and frequency of symptoms in patients with functional dyspepsia (FD). Material and Methods:In total, 150 FD patients were included in this randomized double-blind trial, based on the ROME III diagnostic criteria, and they were divid...

[ 2 ] - Interleukin-17 Serum Levels and TLR4 Polymorphisms in Ulcerative Colitis

Background: Inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including Crohn’s disease and ulcerative colitis (UC). IL-17 has been the target of intensive research in autoimmune diseases. The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 production has also been revealed in UC patients and tissue inflammation in mice. Objectives: To inve...

[ 3 ] - IL-23 Receptor Gene rs7517847 and rs1004819 SNPs in Ulcerative Colitis

Background: Crohn’s disease (CD) and ulcerative colitis (UC) are two major clinical presentations of inflammatory bowel disease (IBD). Many novel candidate genes have been found to be associated with increased risk for IBD. Recently IL-23 receptor gene is identified as an IBD associated gene in genome-wide studies. Objective: To ascertain whether rs7517847 and rs1004819 SNPs in the IL-23 recept...

[ 4 ] - Serum Interleukin-23 Levels in Patients with Ulcerative Colitis

Background: Patients with ulcerative colitis are at increased risk of inflammation. Interleukin 23 (IL-23) is a newly identified cytokine with increased expression in inflamed biopsies of colon mucosa in patients with Crohn's disease; however, there is inconsistent evidence on its role in ulcerative colitis. Objective: We aimed to compare serum IL-23 level in patients with ulcerative colitis an...

[ 5 ] - Clinical Significance of Serum TNF-a and IL-6 Levels in Patients with Metabolic Syndrome

  Background: Several components of metabolic syndrome (MetS) facilitate its diagnosis, including abdominal obesity, hyperlipidemia, high blood pressure, and insulin resistance. The production of tumor necrosis factor-alpha (TNF-alpha) and interleukin 6 (IL-6) seem to be associated with MetS components. The aim of this study was to evaluate the correlation between  the serum levels...

[ 6 ] - فراوانی هلیکوباکتر پیلوری در نمونه کیسه صفرای بیماران کله سیستکتومی شده در بیماران مراجعه کننده به مراکز آموزشی درمانی افضلی پور و باهنر کرمان در سال1394

زمینه و هدف: باکتریهای اپیتلیوم کیسه صفرا و مجاری صفراویمنبع قدرتمندی برای ایجاد بیماریهای کیسه صفرا هستند. از آنجا که ابتلا به عفونت هلیکوباکترپیلوری نقش مهمی درالتهاب مزمن مخاط معده داردوشرایط بروززخم پپتیکوآدنوکارسینوم معده را فراهم می نماید, مطالعات اخیر ارتباط بین این باکتری و کانسر کیسه صفرا را محتمل دانسته اند. هدف تعیین فراوانی هلیکوباکترپیلوری در نمونه کیسه صفرای بیماران مبتلا به کله س...