اثر 8 هفته تمرین مقاومتی با و بدون دانه خرفه بر برخی از نشانگرهای آسیب کبد در زنان مبتلا به دیابت نوع 2

   Background & Aims: Diabetes is a metabolic disease that can lead to liver damage through oxidative stress. Regular physical activity and using purslane as a medicinal plant -due to its anti inflammatory compounds- may be effective in reducing injury. So the purpose of this study was to investigate the effects of 8 weeks of resistance training with and without portulacalo seeds on some of liver injury markers in women with diabetes type 2.  Materials & Methods: In this study, twenty eight sedentary women with T2DM were randomly assigned to four groups of control, training, supplement and training+ supplement. The resistance training program were carried out using resistance bands of varying types at 40-50% of one repetition maximum (1RM), 3 times a week for 8-wk. Subjects in groups 3 and 4 received 7.5 grams of purslane seeds daily. A fasting blood sample was collected as pretest and post-test, followed by 48 hours of physical inactivity and consumption of portulacalo and 12 hours of fasting. Data analysis was performed with paired t-test and ANOVA. (p ≤0 .05).  Result: Eight weeks of the resistance training or portulacalo consumption cause a significant decrease in alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP) levels compared to pretest. However, the effectiveness of combination group (training+supplement) is better in the above indicators as compared with the strategies (training or supplement). Also, a significant decrease in ALT, AST and ALP levels were detected in the training or supplement groups, as compared to the control group. Furthermore, there was a significant decrease in ALT, AST levels in training+ supplement group, as compared with the training or supplement groups. Conclusion: Our findings suggested that using non-drug strategy such as resistance trainings and portulacalo seed consumption improves indicators associated with liver damage in women with diabetes type 2.   SOURCE: URMIA MED J 2015: 25(11): 978 ISSN: 1027-3727