شناسایی و تعیین میزان بیان mRNA دو اسپلایس واریانت گیرنده µ اوپیوئیددی (hMOR-1A و hMOR-1O) در لمفوسیت‌های خون محیطی معتادان ترک‌کرده

شناسایی و تعیین میزان بیان mrna دو اسپلایس واریانت گیرنده µ اوپیوئیددی (hmor-۱a و hmor-۱o) در لمفوسیت های خون محیطی معتادان ترک کرده

زمینه و هدف گیرنده µ اوپیوئیدی در بروز آثار سوء و نیز درمانی اوپیوئیدها مانند مرفین و هرویین نقشی اساسی دارد. این گیرنده در مسیرهای عصبی مربوط به اعتیاد در مغز به میزان زیادی بیان می شود. هدف این مطالعه، یافتن یک بیومارکر محیطی در مطالعات مربوط به اعتیاد از طریق بررسی میزان بیان mrna مربوط به دو اسپلایس واریانت گیرنده µ اوپیوئیدی، یعنـی hmor-1a و hmor-1o در لمفوسیت های خون محیطی معتادان ترک کرد...

Ehrlich-reacting Protein in Kidneys of [hmor-bearing Rats*

A basic protein has been isolated from the kidneys of Jensen sarcoma-bearing Sprague-Dawley rats which is not present in the kidneys of normal animals of the same strain. The purification and isolation of this protein can be analytically followed because it gives a strong colored reaction with Ehrlich reagent. The protein, obtained in crystalline form, has been shown to behave as a single compo...

The Histopathology and Biochemistry of Rats Bearing an Adrenocortical ]hmor

An adrenocortical tumor originating in a female Osborne-Mendel rat was transplanted to intact and adrenalectomized males and to female rats of the same strain. The transplanted tumor grew best in intact males, less in intact females, and least in adrenalectomized males. The following changes characterized the animals bearing this tumor: atrophy of zona fasciculata and zona reticularis of the ad...

ارتباط بیان ژن‌های گیرنده هسته‌ای در سلول‌های خون محیطی با میزان تراکم استخوان در افراد چاق

Studies on the Metabolism of Radioactive Albumin in ]hmor-bearing Rats*

In experiments designed to test the possibility that albumin enters the cells of the Walker ~56 carcinosarcoma as the whole molecule, rather than as free amino acids or peptides, albumin was labeled with each of a variety of C~Mabeled amino acids. The specific activity of the proteins of the whole homogenate was found to be higher than that of the other tissues studied and was found to be the s...

1 Catalytic behavior of alkali - treated Pt / HMOR in n - hexane hydroisomerization

Bifunctional Pt-HMOR catalysts were prepared by incipient wetness impregnation of various desilicated MOR obtained by alkaline treatment using NaOH concentrations ranging from 0.1 to 0.5 M. The zeolite structural changes upon modification were investigated by several techniques including powder X-ray diffraction, Al and Si MAS-NMR spectroscopy, N2 adsorption, pyridine adsorption followed by inf...