A comparative study on the efficacy of combination therapy with Omeprazole and low dose systemic Meglumine Antimoniate (Glucantime) and the full dose systemic Meglumine Antimoniate in the treatment of cutaneous Leishmaniasis

نویسندگان

  • AR Firooz
  • F Jafari
  • MA Nilforoush Zadeh
  • N Ansari
  • Z Nilforoushan
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omparative study of oral azithromycin and systemic meglumine antimoniate (Glucantime) in the treatment of cutaneous leishmaniasis

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cutaneous leishmaniasis is one of the most prevalent endemic disease in Isfahan which is also hyperendemic in other parts of Iran.different treatment have been suddested for cutaneous Ieihmaniasis is glucantim and pentostam,however these drugs have significant side effects and can only be used intravenously.allopurinol is one of the oral medicines suggested for the treatment of cutaneous leishm...

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A comparative study between the efficacy of systemic meglumine antimoniate therapy with standard or low dose plus oral omeprazole in the treatment of cutaneous leishmaniasis.

BACKGROUND & OBJECTIVES Pentavalent antimony compounds are the first line of drugs in the treatment of cutaneous leishmaniasis. However, because of their potential toxic effects, many investigations are performed to find an effective and safe treatment for cutaneous leishmaniasis patients. Our objective in this investigation was to compare the effect of oral omeprazole and low dose systemic meg...

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Comparison of Oral Zinc Sulfate with Systemic Meglumine Antimoniate in the Treatment of Cutaneous Leishmaniasis

The purpose of this study was to investigate comparison between oral zinc sulfate and meglumine antimoniate in the treatment of cutaneous leishmaniasis (CL). So 100 patients with CL were included and randomly divided into two groups. The first group was treated with oral zinc sulfate (10 mg/kg/day during 45 days period), and the second group was treated with systemic meglumine antimoniate (20 m...

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A comparison between intralesional hypertonic Sodium Chloride solution and Meglumine Antimoniate (Glucantime) injections in the treatment of cutaneous Leishmaniasis

Background and objective: Different local and systemic modalities are suggested in the treatment of cutaneous leishmaniasis, but the pentavalent antimony compounds are still considered as the first line of treatment. Regarding to increase in clinical drug resistance and adverse effects, efforts to find a more effective and safer drug is continuing. The objective of this study was to compa...

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عنوان ژورنال

دوره 8  شماره 5

صفحات  340- 346

تاریخ انتشار 2005-10-01

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