Comparative study of bone and lamellar bone formation in Peripheral Giant Cell Granuloma and Peripheral Ossifying Fibroma

Peripheral giant cell granuloma and peripheral ossifying fibroma in children: two case reports.

OBJECTIVES The aim of this study was to present the clinical and histopathological evaluation of reactive gingival lesions, such as peripheral giant cell granuloma (PGCG) and peripheral ossifying fibroma (POF), as exemplified in two cases. CLINICAL PRESENTATION AND INTERVENTION A 12- and a 13-year-old girl were referred to the Department of Pedodontics, both complaining of a painless swelling...

A Comparative Immunohistochemical Study of CD105 Expression in Peripheral and Central Giant Cell Granuloma

Introduction: Despite similar histopathological features, peripheral giant cell granuloma (PGCG) and central giant cell granuloma (CGCG) differ in their biological behavior. PGCG and CGCG are hemorrhagic/vascular lesions, clinically and microscopically. Angiogenesis is necessary for the growth and development of lesions and affects their clinical behavior. CD105 is a useful vascular marker for...

A peripheral giant cell granuloma with extensive osseous metaplasia or a hybrid peripheral giant cell granuloma-peripheral ossifying fibroma: a case report

INTRODUCTION Peripheral giant cell granuloma and peripheral ossifying fibroma are clinicopathologically distinct gingival lesions. Both are included in clinical differential diagnoses of common benign and reactive gingival epulides in humans. It is often impossible to make a clinical distinction between the two entities, thereby making definitive diagnosis dependent on histopathologic features....

Multicentric peripheral ossifying fibroma.

Peripheral ossifying fibroma (POF) is a common solitary gingival growth thought to arise from the periodontal ligament. Though the etiology of POF remains unknown, some investigators consider it an inflammatory or reactive process, while others suggest it is a neoplastic process. In this report, we present and discuss a unique case of multicentric POF, affecting the maxillary and mandibular gin...

Author's response to reviews Title:Peripheral Giant Cell Granuloma with Extensive Osseous Metaplasia, or Hybrid Peripheral Giant Cell Granuloma-Peripheral Ossifying Fibroma: A Case Report Authors:

Peripheral ossifying fibroma

A case of peripheral ossifying fibroma (POF) in the mandibular gingiva of a 17-year-old male is described. The lesion was asymptomatic, firm, pink, and present on the lingual alveolar mucosa interdentally between 43 and 44. Radiographic investigations revealed no significant findings. Excisional biopsy was performed for the lesion. Microscopic findings confirmed the diagnosis of POF.